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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
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Drug ID
ATC Code
DrugBank ID
KEGG ID
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ADR Ontology
ADR Term
Inflammation
ADR ID
BADD_A05823
ADR Hierarchy
08
General disorders and administration site conditions
08.01
General system disorders NEC
08.01.05
Inflammations
08.01.05.007
Inflammation
Description
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. [MeSH]
MedDRA Code
10061218
MeSH ID
D007249
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Inflammation localised | Inflammation localized | Inflammation NOS | Inflammatory reaction | Inflammatory swelling | Inflammation | Exudative inflammation | Inflammations
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Interleukin-1 alpha
P01583
T16340
Interleukin-10
P29456
Not Available
Interleukin-6
P05231
T32578
Interleukin-8
P10145
T22658
Nuclear receptor subfamily 4 group A member 3
Q92570
T93949
Retinol-binding protein 1
P09455
Not Available
Tumor necrosis factor
P01375
T20178
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D02308
Trovafloxacin mesylate
-
-
BADD_D02331
Valsartan
0.000695%
BADD_D02333
Vancomycin hydrochloride
-
-
BADD_D02344
Vemurafenib
0.001949%
BADD_D02345
Venetoclax
0.001066%
BADD_D02352
Verteporfin
-
-
BADD_D02362
Vinflunine
-
-
BADD_D02369
Voriconazole
-
-
BADD_D02373
Warfarin
-
-
BADD_D02378
Zalcitabine
-
-
BADD_D02392
Zoledronic acid
0.426455%
BADD_D02394
Zolpidem
0.000163%
BADD_D02406
Radium ra 223 dichloride
-
BADD_D02412
Octreotide
0.007841%
BADD_D02414
Mesalazine
0.001275%
BADD_D02423
Fondaparinux
0.022614%
BADD_D02426
Ibandronate
0.007117%
BADD_D02433
Salbutamol
0.000039%
BADD_D02434
Cinacalcet
-
-
BADD_D02443
Tiotropium
-
-
BADD_D02450
Crisaborole
0.004832%
BADD_D02451
Pimavanserin
-
-
BADD_D02464
Fingolimod
0.015633%
BADD_D02470
Nintedanib
0.001066%
BADD_D02473
Sodium chloride
0.000906%
BADD_D02486
Niraparib
0.000533%
BADD_D02492
Deflazacort
0.000248%
BADD_D02498
Abemaciclib
0.000533%
BADD_D02510
Rucaparib
-
-
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